Modular Cold Rooms and Stability Chambers
Low and ultra-low temperature environments for all industries
Low and ultra-low temperature environments for every regulated industry. CleanSpace designs, manufactures, and installs modular cold rooms, walk-in cold storage, and stability chambers for pharma, biotech, healthcare, and food and beverage operations. Every project is engineered to GMP, HACCP, and ISO standards, aligned with U.S., EU, and local regulatory requirements, and delivered turnkey through our CleanFit® design-build process with a guaranteed timeline and budget.
Our certifications
Turnkey Cold Room Design, Manufacturing, and Installation
From 2 to 8 °C vaccine and biologic storage to minus 20 °C, minus 40 °C, and ultra-low minus 80 °C environments, CleanSpace is a single-source modular cold room manufacturer and builder. We design, fabricate in our US facility, and install on your site, removing vendor hand-offs, supply-chain delays, and cost overruns.
Precision Temperature and Humidity Control
Redundant cooling systems, validated controls, and continuous monitoring engineered to hold setpoint under real-world load.
US-Manufactured Modular Systems
100% US-made insulated panels, doors, and finishes manufactured in-house. Shorter lead times, tighter quality control, and no reliance on overseas supply chains.
Rapid On-Site Installation
Our CleanFit® process compresses the schedule from design through IQ/OQ validation. Turnkey installation by CleanSpace crews means one accountable partner from concept to qualified handoff.
We have a very demanding project in support of the Project Warp Speed program. We selected CleanSpace because we know they will develop a program to get our project done very rapidly.
Clean spaces for a variety of industries
A Nationwide Partner for Cold Rooms and Cold Chain Design
From ISO 5 aseptic suites to ISO 8 controlled manufacturing environments, CleanSpace is a single-source modular clean room manufacturer and builder. We design, fabricate in our US facility, and install on your site, eliminating vendor hand-offs, supply-chain delays, and cost overruns. From 2 to 8 °C vaccine and biologic storage to minus 20 °C, minus 40 °C, and ultra-low minus 80 °C environments, CleanSpace is a single-source modular cold room manufacturer and builder. We design, fabricate in our US facility, and install on your site, removing vendor hand-offs, supply-chain delays, and cost overruns. Pharma, biotech, healthcare, and food and beverage clients across the United States rely on CleanSpace to deliver GMP and HACCP compliant cold rooms on a predictable timeline and budget. From coastal biotech hubs to Midwest and Southeast distribution centers, CleanSpace brings the same turnkey process, US-made modular systems, and in-house installation crews to every project.
Because we manufacture our modular panel, door, and ceiling systems in the US and self-perform installation, clients anywhere in the country get faster project delivery, consistent quality, and a single point of accountability from kickoff through validation.
Where We Work
Projects delivered coast to coast, including the Northeast biotech corridor, Mid-Atlantic, Southeast, Midwest manufacturing hubs, Texas biomanufacturing centers, the Mountain West, and the West Coast life sciences cluster.
Case Studies
Cold Room Types We Build
Not every cold application needs the same envelope. CleanSpace builds four modular cold room configurations and will recommend the right fit during design:
Walk-In Cold Rooms
Standard and custom walk-ins for vaccines, biologics, reagents, and clinical samples, with redundant refrigeration and continuous monitoring.
Freezer and Ultra-Low Rooms
Minus 20, minus 40, and minus 80 °C environments engineered for biologics, API storage, and advanced therapies.
Stability Chambers
ICH Q1A compliant chambers for pharmaceutical stability testing, validated to exact temperature and humidity setpoints with IQ/OQ documentation.
Hygienic Cold Rooms for Food and Beverage
HACCP-aligned cold storage and processing rooms with cleanable finishes, coved details, and wash-down ready construction.
The CleanFit Process
CleanFit accelerates the design to installation process and is what enables CleanSpace to offer timeline and budget guarantees.
CleanSpace Insights
Improve the speed and efficiency, provoke dialogue for alignment and consider key decision points as you prepare for your next project.
Cold Room FAQs
What is a modular cold room?
A modular cold room is a prefabricated, insulated, temperature-controlled environment built from engineered panel systems. Unlike stick-built cold storage, modular cold rooms install faster, can be reconfigured as processes change, and deliver consistent GMP and HACCP performance.
What temperature ranges does CleanSpace design to?
We routinely design and build controlled room temperature (15 to 25 °C), refrigerated (2 to 8 °C), frozen (minus 20 and minus 40 °C), and ultra-low (minus 80 °C) environments, along with ICH-compliant stability chambers.
Are CleanSpace cold rooms GMP and HACCP compliant?
Yes. Every cold room is engineered to meet GMP, HACCP, FDA, and applicable EU requirements, with documentation to support IQ, OQ, and PQ validation.
Do you build stability chambers?
Yes. CleanSpace designs and installs ICH Q1A compliant stability chambers at standard setpoints (25 °C / 60% RH, 30 °C / 65% RH, 40 °C / 75% RH) and custom profiles for pharmaceutical stability testing.
Do you serve clients nationwide?
Yes. CleanSpace serves clients across the United States with US-based manufacturing and self-performed installation crews supporting every major life sciences, healthcare, and food and beverage region.
How long does it take to build a modular cold room?
CleanFit® typically delivers a modular cold room or stability chamber in a fraction of the time of conventional construction, moving from design to validated handoff in weeks rather than many months.
How much does a cold room cost?
Cost depends on temperature range, square footage, redundancy, monitoring, and equipment integration. CleanFit® provides a fixed-price, guaranteed-timeline quote after a scoping session.